Artane (trihexyphendyl HCI)

Parkinson's Disease Medications

What are the Uses?: Trihexyphendyl HCL, or Artane is used to treat:

Parkinson's Disease

Artane (trihexyphendyl HCI) is used to treat the symptoms of Parkinson's Disease and to relieve the side effects of parkinsonism, akinesia and dystonia which are caused by antipsychotic medications.

When Will My Medication Start to Work?: Artane (trihexyphendyl HCL) can begin to relieve PD symptoms in an hour but onset varies greatly in many individuals. Some individuals do not experience any therapeutic effects for several months. Consult your doctor if this is a concern.

Are there any Drug Interactions?: Remember, always follow your physician's recommendations on how to take your medication. Even if you are taking one of the following substances, continue taking your medication as prescribed and consult your physician. Also, if you are taking any other prescription medications, herbal remedies, vitamins, and/or over-the-counter medications, be sure to tell your physician.

Any Other Important Information?: Pregnancy and Breastfeeding Issues: If you are pregnant, plan to become pregnant, or breastfeeding, discuss the potential risks of this or any medication with your doctor.

Older patients, particularly over the age of 60, develop sensitivity to Artane and may require a dosage change. Patients with liver, heart, kidney problems, or high blood pressure (hypertension) should be monitored while taking Artane.

In addition to the information listed above, there may be other important issues or precautions related to this medication. For further information, you can ask your prescribing doctor or therapist.

Side Effect Information: Remember that only some people will experience side effects--and that no one experiences side effects in exactly the same way. If you experience any side effects, contact your doctor or clinician right away and continue taking your medication. The following list may not contain all of the side effects associated with this medication:
Most common side effects anxiety/nervousness, blurry vision, dry mouth, nausea
Infrequent side effects constipation, urinary retention, weakness
Rare side effects/Risks anticholinergic intoxication, tardive dyskinesia (involuntary movements)

Side-effects and risks other than those listed above may also occur. Talk to your prescribing doctor or therapist about any potential or existing side-effects that you’re concerned about.

Every effort has been made to ensure that the information provided by is accurate and up-to-date, but no guarantee is made to that effect.’s medication information is a reference resource designed as a supplement to, and not a substitute for, the expertise, skill, knowledge, and judgment of healthcare practitioners in patient care. does not assume any responsibility for any aspect of healthcare administered with the aid of information provides.