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Alzheimer's and Dementia
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Understanding Just What a Diagnosis of Alzheimer's Can Mean

In a Gallup poll commissioned by the Alzheimer's Association, 1 in 10 Americans said that they had a family member with Alzheimer's and 1 in 3 knew someone with the disease. Alzheimer's is a devastating disorder of the brain's nerve cells that progressively impairs memory, thinking, and behavior. While there's not yet a cure, there are treatments and everyday management techniques that can improve the quality of life for those with Alzheimer's and help those who love and care for them.
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Promoting Independence in Those Who Have Alzheimer's

In The 36-Hour Day, one of the first books on Alzheimer's from the caregiver's perspective, Nancy Mace and Peter Rabins devote several chapters to coping with the symptoms of Alzheimer's disease. "Some people fall when they first get out of bed," they write. "Have the person sit on the edge of the bed for a few minutes before walking."

When Caring for Someone With Alzheimer's Disease...

People with Alzheimer's disease have specific needs and offer special challenges to those who care for them. Read about some of the things that can be done to make everyday living a little more manageable--for your loved one, as well as for yourself.

Simple Verbal Memory Test May Be Best Indicator of Pre-Symptom Alzheimer's

Because there's currently no cure and just several drugs that can help stave off the devastating symptoms when taken early in the disease, early diagnosis of Alzheimer's is an area of research generating considerable attention. Some of the most recent studies have found that verbal memory tests may be the best overall predictor of pre- and early-symptom Alzheimer's.

Chance Encounters

By Dr. Bradley Olson

The events of that day so long ago which I thought to be miraculous were not, and the seemingly everyday, conversational leave-takings of my family, which I naively believed to be merely ordinary, were truly extraordinary. Hardly a day goes by when I don’t think of my grandmother or her legacy and in some way or another, however briefly, I miss her with all the conviction a 10-year-old heart can conjure…

Could It Be Alzheimer's? 10 Possible Early Warning Signs

It's normal to every once in a while forget a phone number, the day of the week, or what you just came in to a room to do. Memory changes, confusion, and disorientation associated with Alzheimer's, however, grow progressively worse over time. The early-stage warning signs may develop gradually and go unnoticed, or, in many cases, they're initially mistaken for the normal aging process.


In the News


Antipsychotic Medications May Ease Some Alzheimer’s Symptoms, Not Others

Antipsychotic medications may lessen symptoms like hostility and aggression in patients with Alzheimer’s disease, but do not appear to lessen other symptoms or improve quality of life, according to a recent analysis of data from the Clinical Antipsychotic Trials of Intervention Effectiveness Alzheimer’s Disease (CATIE-AD) study. The analysis was published June 2, 2008, in the American Journal of Psychiatry.

Alzheimer's Disease (AD) Fact Sheet

Scientists think that as many as 4.5 million Americans suffer from AD. The disease usually begins after age 60, and risk goes up with age. While younger people also may get AD, it is much less common. About 5 percent of men and women ages 65 to 74 have AD, and nearly half of those age 85 and older may have the disease. It is important to note, however, that AD is not a normal part of aging.

Cortex Area Thinner in Youth with Alzheimer's-Related Gene

A just-released brain imaging study has found that part of the brain first affected by Alzheimer's disease is thinner in youth with a risk gene for the disorder. A thinner entorhinal cortex, a structure in the lower middle part of the brain's outer mantle, may render these youth more susceptible to degenerative changes and mental decline later in life.

Marijuana Ingredient May Slow Alzheimer's, Study Says

Cadaver and animal studies suggest that cannabinoids found in marijuana may reduce inflammation related to Alzheimer's disease and perhaps slow progression of the disease itself.

Study Boosts Confidence in Potential Screening Tool for Alzheimer's Disease

A major study has confirmed the value of potential markers for identifying people with Alzheimer's disease. Scientists are hopeful that biomarkers will eventually be developed to help detect incipient illness in younger people who are at risk of the disease but who may not yet show any symptoms.

New Test Developed to Determine Onset of Alzheimer's

Researchers at the University of California at Los Angeles say they have created the first test that can record the onset of Alzheimer's disease. It’s currently estimated that Alzheimer's, a degenerative brain disease that causes memory loss, disorientation, depression and decay of bodily functions, affects as many as 4 million Americans.

Alzheimer's Disease--Symptoms and Diagnosis

An early, accurate diagnosis of Alzheimer's disease helps patients and their families plan for the future. It gives them time to discuss care options while the patient can still take part in making decisions. And even though no drug can slow the onset or the progression of Alzheimer's, early diagnosis offers the best chance to treat the symptoms of the disease.

New Study Boosts Confidence in Potential Screening Tool for Alzheimer's Disease

A major study has confirmed the value of potential markers for identifying people with Alzheimer's disease. Scientists found that levels of two key indicators in spinal fluid distinguished clinically diagnosed Alzheimer's patients from controls with 89-92 percent efficiency.

How a Common Gene Influences Memory

Researchers searching for a possible brain derived neurotrophic factor (BDNF) connection with the memory problems and hippocampal changes of Alzheimer's disease, depression and normal aging have shown that a common gene variant influences memory for events in humans by altering a growth factor in the brain's memory hub.

Avoiding Caregiver Burnout

Dealing with illness and its different stages--whether temporary or long-term, whether the brain is affected or another part of the body--brings on challenges and pulls on many different emotions for the individual who's personally affected, as well as for the family members dedicated to caring for them. It's important to know how best to regulate these feelings.

Lithium Shows Promise Against Alzheimer’s in Studies With Mice

Studies in mice and cells suggest an enzyme crucial to formation of Alzheimer’s plaques and tangles may hold promise as a target for future medications. By blocking the enzyme, lithium stems the accumulation of beta amyloid which would eventually form Alzheimer’s plaques.

Antipsychotic Medications Used to Treat Alzheimer’s Patients Not as Promising as Hoped

According to study published in the October 12, 2006, issue of the New England Journal of Medicine, commonly prescribed antipsychotic medications used to treat Alzheimer's patients with delusions, aggression, hallucinations, and other similar symptoms appears to be no more effective than a placebo.

Gene Modifying Study Shedding New Light on Alzheimer's and Other Neuro-Degenerative Diseases

In a University of Rochester laboratory study that could help in deciphering neuro-degenerative diseases such as Alzheimer's and Parkinson's, scientists are finding that genetically altered mice learned and remembered better when subjected to tricky maze exercises.

Newborns’ Umbilical Cords May Provide Cells For Repairing Brains Damaged By Strokes, Alzheimer’s and Other Neurological Ills

Free of the ethical concerns surrounding the use of fetal tissue, umbilical cords discarded after birth could provide a vast new source of repair material for fixing brains damaged by Alzheimer’s disease, and other neurological disorders.

Recent Imaging Study Shows How Cholinesterase Inhibitor Improves Working Memory

The results of a new study indicate that the way cholinesterase inhibitors may improve memory is by enhancing the selectivity of perceptual processing that is to be remembered. Enhanced perception produces more vivid memories, and thus simplifies the processing demands for memory maintenance and retrieval.

 





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